Olig2 astrocyte
Web14. jan 2024. · Elevated BMP-2 levels are translated into a rapid increase in Id3 expression in adult NSPC subpopulations, specifically in Olig2+ C cells and Thbs4+ SVZ-born astrocytes. Id3 then heterodimerizes with the bHLH transcription factor E47 and releases E47-mediated repression of astrocyte-specific gene expression. Web16. avg 2024. · Diversity in astrocyte morphology and gene expression, as revealed by transcriptional analysis, is well-recognized and has been reported in several CNS pathologies, including ischemic stroke, CNS demyelination, and traumatic injury. ... Olig2+, and P0+ cells following contusion SCI in mice. Oligodendrocyte precursor cells (OPCs; …
Olig2 astrocyte
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Web08. nov 2024. · We have reported that the transcription factor Olig2 labels a subpopulation of astrocytes (Olig2-astrocytes), which show distribution patterns different from those of … Web23. jul 2013. · Furthermore, by using a spatiotemporally specific conditional ablation approach, Olig2 is shown to have a crucial role in astrocyte development in the entire …
WebInvitrogen Anti-OLIG2 Monoclonal (1G11), Catalog # MA5-15810. Tested in Western Blot (WB), Immunocytochemistry (ICC/IF), Immunohistochemistry (IHC) and ELISA (ELISA) applications. ... (magenta) and OLIG2 (green) at stages of neuronal differentiation from neural stem cells. The cells were stained with astrocyte marker GFAP and … Web星形胶质细胞(Astrocyte) 最大的神经胶质细胞,胞体直径3-5微米,核呈圆球形常位于中央,淡染。它有许多长突起,其中一个或几个伸向邻近的毛细血管,突起的末端膨大形成血管足突,围绕血管的内皮基膜形成一层胶质膜。星形细胞又分为原浆型和纤维型两种。
Web24. okt 2003. · Together, these results reveal a novel molecular function of OLIG2 on the astrocyte development. In the developing vertebrate nervous system, multipotent neural …
OPCs are a population of glial cells in the CNS which comprise about 5% of total cells and are the main proliferating cell type in the resting state of adult CNS [11]. In the adult CNS, OPCs can differentiate into myelinating oligodendrocytes and are usually characterized as NG2 proteoglycan expressing cells. … Pogledajte više Oligodendrocytes are myelinating cells that are differentiated from OPCs under the control of bHLH transcriptional factor Olig2 [17]. Besides OPCs, we also analyzed the … Pogledajte više After discovering remarkable Olig2 expression in astrocytes within some specific regions, we further investigated whether the Olig2 expression level in astrocytes is … Pogledajte više Neurons are electrically excitable cells that are the basic functional units of the CNS. Olig2 plays a crucial role in the generation of motor … Pogledajte više Astrocytes are resident glial cells in the CNS besides oligodendrocytes and microglia. We further investigated whether Olig2 expression can be detected in the astrocytes of adult CNS by performing co-immunostaining … Pogledajte više
Web15. maj 2007. · The mechanisms underlying astrocyte heterogeneity in the developing mouse brain are poorly understood. The bHLH transcription factor Olig2 is essential for … small power bankWeb22. okt 2008. · In addition, cortical Olig2 ablation results in a decrease in proliferation of reactive astrocytes in response to injury. Cell-type-specific mutagenesis indicates that … highlights ppt template freeWebOlig2 directs astrocyte and oligodendrocyte formation in postnatal subventricular zone cells. J Neurosci. 25(32): 7289-98, 2005. (PMID: 16093378) 6) Uchida Y, Nakano S, Gomi F, Takahashi H. Differential regulation of basic helix-loop-helix factors Mash1 and Olig2 by beta-amyloid accelerates both differentiation and death of cultured neural stem ... highlights powderWebThe presence of astrocyte-like SOX9+ and oligodendrocyte-like OLIG1+ cells in grade II IDH1-mutant gliomas raises new questions about their role in the pathology. ... In oligodendrogliomas, cells express the transcription factors MYT1, Nkx2.2, Olig1, Olig2, Sox8, four receptors (EGFR, PDGFRα, LIFR, PTPRZ1) but not the co-receptor NG2 … small power amplifierWeb包含至少一个检索词. 不包含检索词. 出现检索词的位置 highlights powerpoint templateWebIt is thought to be a necessary factor for oligodendrocyte progenitor cell commitment to an oligodendrocyte fate, along with the related factor Olig2. Olig1-null mice brains show impaired oligodendrocyte differentiation, though compensatory increased Olig2 expression may decrease the phenotype severity. Target information from Dai et al., 2015.. small power bank caseWeb1 day ago · Markers of astrocyte precursors are not enriched in IDH-mutant gliomas. Our studies show that despite differences in clinical manifestation and genomic alterations, all IDH-mutant gliomas resemble early stages of oligodendrocyte lineage and are stalled in oligodendrocyte differentiation due to blocked myelination program. ... OLIG1, OLIG2 ... highlights portugal vs switzerland